Scientific Evidence
Review a structured summary of the available scientific materials, kept distinct from E-Cream's current cosmetic positioning.
Review the evidenceCosmetic Topical CreamProduct Documentation & Testing
ErpeCream
ErpeCream is the principal brand of ACS Biomed's botanical topical cosmetic formulation. For specific markets, the formulation may also be presented under the E-Cream name according to applicable local requirements. The product is supported by cosmetic safety documentation, microbiological testing and stability evaluation.
Made in Italy
ErpeCream
E-Cream
Market-Specific Branding
International Branding & Market Adaptation
ACS Biomed adopts a flexible, market-specific branding approach to support the international commercialization of its cosmetic portfolio. Depending on local regulatory requirements and the outcome of applicable assessments, the product may be commercialized under the ErpeCream denominations.
Commercial naming and product labeling are subject to applicable local regulatory requirements.
Documented Scientific Evidence — ErpeCream
ErpeCream identifies the cosmetic product and the scientific research on the formulation. The separate ErpeCream Investigational Pharmaceutical Development Programme is presented independently.
The following content summarises completed experimental research and documented laboratory results. In vitro findings are presented within the study model and conditions; they do not constitute established cosmetic effects or approved medicinal indications.
1
Viral Entry Block
Nanoemulsion particles create a physical barrier that prevents HSV virions from attaching to epithelial cells.
2
Direct Antiviral Action
Botanical actives interfere with HSV replication cycle, reducing viral load at the site of infection.
3
Local Immunomodulation
Reduction of TNF-α, IL-6, and oxidative stress markers. Supports local immune response without systemic exposure.
4
Tissue Repair
Accelerates epithelial barrier restoration and tissue healing, contributing to faster lesion resolution.
Formulation
Measured Physicochemical Characteristics
This content describes the developed and characterised formulation and technical data measured under the applied analytical conditions; it is not a claim of cosmetic effects.
O/W Nanoemulsion — Research Data
120 ± 30 nm
Droplet diameter
-35 mV
Zeta Potential
5.5
pH
320 mOsm/kg
Osmolality
Compatible with vaginal mucosa • Iso-osmotic • High stability
Botanical Ingredients in the Research Programme
Open each card to view the role described in research materials.
Fenugreek
Trigonella Foenum-graecum
SoothingView research note
Fenugreek
Research noteSoothing and protective action on mucosa. Reduces irritation and promotes comfort during application.
Oak Gall
Quercus Infectoria
Astringent, AntimicrobialView research note
Oak Gall
Research noteAstringent and antimicrobial properties. Contributes to local microbial proliferation control.
Pueraria
Pueraria Mirifica
AntiviralView research note
Pueraria
Research noteDocumented antiviral activity. Supports the body's natural response against viral infections.
Witch Hazel
Hamamelis Virginiana
Soothing, AstringentView research note
Witch Hazel
Research noteCombination of soothing and astringent properties. Calms irritation and promotes tissue healing.
Ginseng
Panax Ginseng
ImmunostimulantView research note
Ginseng
Research noteImmunostimulant action. Enhances local immune defenses for a more effective response.
Echinacea
Echinacea Angustifolia
Immune SupportView research note
Echinacea
Research noteRecognized immune support. Stimulates macrophage activity and protective cytokine production.
Research Formulation Excipients
Sweet almond & jojoba oil
Emollients
Vitamin E
Antioxidant
Glycerol
Moisturizer
Completed Exploratory Clinical Study — ErpeCream
Completed open-label exploratory study, n=42. Non-head-to-head comparison; comparator response rates are from published literature. Reported study results do not establish an approved medicinal indication or cosmetic efficacy.
ErpeCream — Product Information
Cosmetic topical creamSelected botanical ingredientsCosmetic safety documentationMicrobiological testingStability evaluation5 ml airless dispenser
Cosmetic Product and Investigational Research
COSMETIC PRODUCT
ErpeCream — Cosmetic Topical Cream
Proprietary botanical formulation supported by cosmetic safety documentation, microbiological testing and stability evaluation.
Commercial availability is subject to applicable local regulatory requirements.
ErpeCream
INVESTIGATIONAL PHARMACEUTICAL DEVELOPMENT
Separate Pharmaceutical Development Pathway
- Phase IIb materials: Prior development materials describe an 80-patient head-to-head study versus acyclovir, with PPD (Thermo Fisher Scientific) as CRO. Ref: BC147404-01. Current study status and recruitment are not stated.
- Phase III materials: Prior materials describe a proposed design involving 420 patients, 7 EU countries, 25 sites and an approximate 29-month timeline; current status requires documentary verification.
- Pathway: A separate pharmaceutical pathway; no approved medicinal indication is claimed.
ErpeCream — Product Information
ErpeCream Product Specifications
Product information and directions from the approved packaging.
| Specification | ErpeCream |
|---|---|
| Category | Cosmetic topical cream |
| Pack format | 5 ml airless dispenser |
| Application | Apply a thin layer to the desired skin area and massage gently until fully absorbed. |
| Frequency | Twice a day or as needed. |
| Product support | Cosmetic safety documentation, microbiological testing and stability evaluation. |
| Commercialization | Subject to applicable local regulatory requirements. |
Pharmaceutical Development
ErpeCream refers to a separate investigational pharmaceutical programme. This section does not present E-Cream as an approved medicine.
Explore the programmeContact ACS Biomed to discuss international distribution opportunities for ErpeCream, subject to applicable market-specific regulatory requirements.
Product support includes cosmetic safety documentation, microbiological testing and stability evaluation.
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Target Channels
Pharmacy chains (OTC)Dermatology distributorsE-commerce platformsWholesalersBeauty & wellness retailers
Benefits for Distributors
- Cosmetic notifications documented; market-specific launch readiness subject to local requirements
- 36-month / ICH Zone IVb results apply to the tested ErpeCream formulation and 5 ml airless presentation
- Cosmetic positioning; OTC status depends on the destination market
- Differentiated positioning; no broad market-equivalence claim made
- Made in Italy
- Full marketing material support
Partnership Options
Regional or Global Licensing
Post-Phase IIb readout licensing for specific territories or global rights
Phase III Co-Development
Joint investment in pivotal Phase III program. Shared risk/reward.
Strategic Acquisition
Full asset or company acquisition. IP + data room available.
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Scientific and clinical information about the ErpeCream programme on this page is historical and investigational. Findings are presented with available study context and limitations; they do not establish an approved medicinal indication or efficacy for the E-Cream cosmetic product. The current status of planned or referenced clinical studies requires documentary verification.